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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61424
Doc. No : 74A
Main Entry : BANDYOPADHYAY S.*
Title & Author : ANTIFERTILITY ACTIVITY OF METHANOL EXTRACT OF BASSIA LATIFOLIA AND CAJANUS CAJAN IN FEMALE ALBINO MICE OVARIES [Article]
Title : IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)
Volume Number : , Vol.9 ؛ No.2
Date : , (2010)
page : : 0 - 0
Abstract : Bassia latifolia bud and Cajanus cajan seed were evaluated for antifertility activity in mature female mice. Antifertility activity was evaluated by observing the estrus cycle, body weight, wet weight of ovaries, steroidogenic enzymes, and substrates. Bassia latifolia bud and Cajanus cajan seed extract arrested normal oestrous cycle at dioestrous stage. The decrease in weight of ovary and uterus after methanol extracts of Bassia latifolia bud and Cajanus cajan seed treated mice is related to inhibition of ovarian steroidogenesis in mature female mice. The accumulation of total cholesterol and ascorbic acid in the ovaries of the mature female mice also indicates the inhibition of ovarian steroidogenesis due to the reduced activity of Glucose-6-Phosphate Dehydrogenase and D5 -3b-Hydroxysteroid Dehydrogenase. The oestrus cycle of the extract treated mice resumes to normal after 28 and 42 days respectively for both the plants. Thus the antifertility activities were found to be reversible
Descriptor : CONSTITUENTS
Descriptor : ESSENTIAL OIL
Descriptor : FERULA GUMMOSA
Descriptor : SEIZURE PROTEC
 
 
 
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