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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61440
Doc. No : 90A
Main Entry : BHALKE R.D.*
Title & Author : ANTINOCICEPTIVE ACTIVITY OF TRIGONELLA FOENUM-GRAECUM LEAVES AND SEEDS (FABACEAE) [Article]
Title : IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)
Volume Number : , Vol.8 ؛ No.2
Date : , (2009)
page : : 57 - 59
Abstract : Present study reports effect of petroleum ether, chloroform, ethyl acetate and methanolic extracts of leaves and seeds of Trigonella foenum-graecum Linn. )Fabaceae( on nociceptive response using hot plate method and writhing test in mice. All the extracts of Trigonella foenum-graecum showed significant central and peripheral analgesic activity in hot plate method and acetic acid-induced writhing test, respectively, at the dose of 50 mg/kg intraperitoneally. Methanolic extract of leaves of Trigonella foenum-graecum showed highest increase in reaction time in hot plate method and more inhibitory effect on writhing induced by acetic acid. Pentazocin and paracetamol was taken as standard for hot plate and writhing model respectively.
Descriptor : TRIGONELLA FOENUM-GRAECUM
Descriptor : ANALGESIC ACTIVITY
Descriptor : HOT PLATE MODEL
Descriptor : ACETIC ACID INDUCED WRITHING MODEL
 
 
 
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