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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61443
Doc. No : 93A
Main Entry : SAYAH M.
Title & Author : ANTI-NOCICEPTIVE EFFECT OF THE FRUIT ESSENTIAL OIL OF CUMINUM CYMINUM L. IN RAT [Article]
Title : IRANIAN BIOMEDICAL JOURNAL
Volume Number : , Vol.6 ؛ No.4
Date : , (2002)
page : : 141 - 145
Abstract : Cuminum cyminum Linn. )Umbelliferae( is a plant, which has been used as a toothache remedy in folk medicine of Iran. In this study, the potential anti-nociceptive and anti-inflammatory activities of the fruit essential oil of C. cyminum has been evaluated in chemical )formalin test( and thermal )tail-flick test( models of nociception and formalin model of acute inflammation in rats and mice. The essential oil at the doses ranging between 0.0125 and 0.20 ml/kg exhibited a significant and dose-dependent analgesic effect in the model of chronic and inflammatory pain. However, the essential oil was devoid of anti-inflammatory activity. Moreover, the essential oil had no analgesic effect in tail flick test as a model of acute pain. The LD50 value of 0.59 ml/kg was obtained for the essential oil. This low toxicity of the essential oil makes it worthy for further studies
Descriptor : ANTI-NOCICEPTIVE EFFECT
Descriptor : ESSENTIAL OIL
Descriptor : CUMINUM CYMINUM LIN
Added Entry : PEIROUVI A.,
: KAMALINEZHAD M
 
 
 
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