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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61457
Doc. No : 107A
Main Entry : AHMED M.F
Title & Author : ANTIOXIDATIVE ACTIVITY OF MELIA AZEDARACH LINN LEAF EXTRACT [Article]; ZAMEERUDDIN K.,IBRAHIM M.
Title : IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)
Volume Number : , Vol.7 ؛ No.1
Date : , (2008)
page : : 31 - 34
Abstract : The antioxidant activity of the melia azedarach was investigated in rats with ethanol-induced erythrocyte damage. Chronic administration of ethanol )20percent w/v, 2 g/kg.p.o., daily for four weeks( increased the level of lipid peroxidation )LPO(, decreased the activity of superoxide dismutase )SOD( and catalase and reduced the content of glutathione )GSH(. The concurrent treatment of ethanol-administered rats with melia azedarach )500mg/kg, p.o.( prevented the ethanol-induced changes and the effect was compared with combination of vitamin E and C. It can, therefore, be suggested that the leaves of melia azedarach posses an erythrocyte protective activity against drug-induced oxidative stress.
Descriptor : MELIA AZEDARACH
Descriptor : ANTIOXIDANT ACTIVITY
Descriptor : ETHANOL
Descriptor : OXIDATIVE STRESS The antioxidant activity of the melia azedarach was investigated in rats with ethanol-induced erythrocyte damage. Chronic administration of ethanol (20
Descriptor : w/v
Descriptor : 2 g/kg.p.o.
Descriptor : daily for four weeks) increased the level of lipid peroxidation (LPO)
Descriptor : decreased the activity of superoxide dismutase (SOD) and catalase and reduced the content of glutathione (GSH). The concurrent treatment of ethanol-administered rats with melia azedarach (500mg/kg
Descriptor : p.o.) prevented the ethanol-induced changes and the effect was compared with combination of vitamin E and C. It can
Descriptor : therefore
Descriptor : be suggested that the leaves of melia azedarach posses an erythrocyte protective activity against drug-induced oxidative stress. Keyword: MELIA AZEDARACH
Descriptor : ANTIOXIDANT ACTIVITY
Descriptor : ETHANOL
 
 
 
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