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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61513
Doc. No : 163A
Main Entry : MOHAMMADI R
Title & Author : AUTOANTIBODIES AGAINST MODIFIED LOW DENSITY LIPOPROTEIN IN PATIENTS WITH CORONARY HEART DISEASE AND NORMAL INDIVIDUALS [Article]; SARRAFNEJAD A.,KARIMI A.,MOHAGHEGHI A.
Title : ACTA MEDICA IRANICA
Volume Number : , Vol.39 ؛ No.4
Date : , (2001)
page : : 191 - 194
Abstract : Different classes of autoantibodies against two antigenic forms of modified low density lipoprotein )mod-LDL( were detected in 140 patients by indirect ELISa method. Investigated autoantibodes included total immunoglobulins )IgT(. Immunoglobulin G )IgG(, and immunoglobulin M )IgM( against oxidized LDL with copper ions )ox-LDL( and modified LDL with malondialdehyde )mal-LDL( )IgT-O( IgT against mal-LDL )IgT-M(, IgG against ox-LDL )IgG-O(, IgM against ox-LDL )IgM-o(, and IgM against mal-LDL )IgM-M( were significantly )P<0.05( higher in patient with coronary atherosclerosis than normal individuals, whereas titer of IgG against mal-LDl )IgG-M( didnعt show any significan difference between these groups. In this study, no correlation was found between autoantibody titers and severity of coronary artery stenosis. The results indicate that titers of these autoantibodies are dependent on an active atherogenic process
Descriptor : ATHEROSCLEROSIS
Descriptor : AUTOANTIBODIES
Descriptor : LDL MODIFICATION
Descriptor : MOD-LDL
Descriptor : OX-LDL
Descriptor : MAL-LDL
Added Entry : DOUSTI M.,
: JAVADI E
 
 
 
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