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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61519
Doc. No : 169A
Main Entry : BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN
Title & Author : BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN [Article]; MOHAMMAD K.,GOLESTAN B.,CHAMARI M
Title : ACTA MEDICA IRANICA
Volume Number : , Vol.40 ؛ No.3
Date : , (2002)
page : : 181 - 186
Abstract : Hyperandrogenism affects 2-6percent of all women. Hypertension is one of disturbances which is related to androgen excess. Higher intakes of vitamin C and vitamin E have been associated with lower blood pressure. Tho investigate the effect of these vitamin supplementation on blood pressure in hyperandrogenic women, a randomized, double-blind, placebo-controlled study was designed on 56 women 18-54 years old. Women were randomly allocated to one of four treatment groups: spironolactone plus vitamain C and viamin E )SCE(, spironolactone plus vitamins placebo )SP(, vitamin C plus vitamin E )CE(, vitamins placebo )P(. The treatment consisted of oral administration of 100 mg spironolactone, 1000 mg vitamin C and 900 mg vitamin E )alpha-tocopherol acetate( daily for about 3 months. Results indicated that compared to pretreatment, vitamins supplementation significantly lowered systolic )119.1▒آ12.6 vs. 112.6▒آ15.4 mmHg( and mean blood pressure )97.4▒آ11.5 vs. 92.▒آ 12.1 mmHg( SCE group )P<0.05(, diastolic )87.3▒آ12.7 vs. 80▒آ12 mmHg( and mean group )P<0.05(. Blood levels of vitamin C and alpha-tocopherol increased in all SCE and CE subjects. In conclusion, vitamin C and vitamin E supplementation reduced blood pressure in hperandrogenic women who are at risk of hypertension.
Descriptor : VITAMIN C
Descriptor : VITAMIN E
Descriptor : BLOOD PRESSURE
Descriptor : ANDROGEN EXCESS
Added Entry : SIASI F.,
: MIRDAMADI S.R.,
 
 
 
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