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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61650
Doc. No : 301A
Main Entry : NAJAR PIRAYEH SH
Title & Author : DETECTION OF UREAPLASMA UREALYTICUM IN CLINICAL SAMPLES FROM INFERTILE WOMEN BY POLYMERASE CHAIN REACTION [Article]
Title : IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)
Volume Number : , Vol.6 ؛ No.1
Date : , (2007)
page : : 23 - 26
Abstract : Genital Ureaplasma urealyticum infection is considered to be a sexually transmitted infection. The bacterium has been found to be involved in PID, chorioamnionitis, urethritis, respiratory distress syndrome and pneumonia in newborn, abortion and infertility. U. urealyticum infections not only jeopardize fertility but also pose a risk for infertility treatment and resulting pregnancies. The purpose of this study was to de-termine the prevalence of U. urealyticum in specimens from infertile women by polymerase chain reaction )PCR(. 377 endocervical swab samples were taken from infertile women. Mycoplasma genus and U. urealyticum were detected by means of the polymerase chain reaction with specific primers. Mycoplasma genus DNA was detected in specimens from 141 )37.4percent( of 377 patients. Of these 141 patients 85 )22.5percent of total specimens( were PCR positive with urease gene primers for U. urealyticum. The isolation rate of U. urealyticum in young women )<30 age( was higher than the others. Because of the potential adverse effects of U. urealyticum on the success rate of highly specialized infertility treatment, and its causal roles in several maternal complications of pregnancy and in neonatal morbidity and mortality, the rapid detec-tion of U. urealyticum by PCR in infertile women could be important and necessary. The increased sensi-tivity and shorter time requirement of PCR support its further development for the diagnosis of U. urealyti-cum infections.
Descriptor : UREAPLASMA UREALYTICUM
Descriptor : MYCOPLASMA
Descriptor : INFERTILITY
Descriptor : PCR
Added Entry : SAMIMI R.
 
 
 
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