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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61676
Doc. No : 327A
Main Entry : DERAKHSHAN A
Title & Author : DISORDERS OF GROWTH AND BONE MINERAL DENSITY IN PEDIATRIC RENAL TRANSPLANT RECIPIENTS (POSTER PRESENTATIONS: P117) [Article]; FALAHZADEH ABARGHOUEI M.H.,BASIRATNIA M.,HOSSEINI ALHASHEMI GH.
Title : IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)
Volume Number : , Vol.3 ؛ No.SUPPLEMENT 1
Date : , (2009)
page : : 15 - 15
Abstract : Introduction. Incomplete resolution of CKD-associated abnormalities of bone and mineral metabolism results in the relatively high prevalence of renal osteodystrophy )ROD( in pediatric kidney recipients. Methods. This is a non-randomized, cross-sectional, and analytic-descriptive study on bone growth and density in 57 children and adolescents who had received 60 renal allografts before the age of 20 years in Shiraz, Iran. The patients عheight and weight were measured and their bones evaluated byع conventional left handwrist radiography عandع bone mineral densitometry )BMD ع(by dual-energy X-ray absorptiometry )DEXA( technique. Advanced specialized software that could adjust all measured scales of BMD for pediatric agegroup, gender, and patients عBMI )weight and height( was used to determine BMD Z-score. SPSS software version 15 was used for statistical calculations and analyses. P value less than 0.05 was considered as significant. Results. We studied 27 )47.4percent( male and 30 )52.6percent( female patients with mean age of 18.7 ▒آ 4.25 )range, 9 to 27 years( years old. The patients had a well functioning renal allograft for a meann period of 67.1 ▒آ 33.8 )range, 6 to 132 months( months after transplantation. Mean age at transplantation was 13.1 ▒آ 3.46 )range, 4.5 to 20 years( years. They had a past history of CKD lasting for a mean period of 32.4 ▒آ 25.8 )range, 3 to 108months( months before transplantation that included a period of regular hemodialysis in 44 out of 57 )77.2percent( cases for a mean period of 13.5 ▒آ 12.8 )range, 2 to 60months( months. The patients height was 149.4 ▒آ 11.1 )range, 116 to 172 cm( centimeters while their mean height age and bone age were 11.9 ▒آ 1.8 )range, 6 to 15.5( and 15.6 ▒آ 3.3 )range, 7 to 19( years, showing a mean height age and bone age retardation of 5.7 ▒آ 2.3 )range, 0.5 to 10.5( and 1.22 ▒آ 1.47 )range, 0 to 7( years; respectively, if compared with their chronological age [Height age < Bone age < Chronological age; 2-tailed, P < 0.001(. Height age retardation was more significant than bone age retardation )2-tailed, P < 0.001(. Although left handwrist radiography was clearly normal in 46 )80.7percent( cases and showed osteopenia in 11 )19.3percent( patients, none of the other radiologic signs of ROD were seen. The patients عBMD Z-scores were determined to be -1.77 ▒آ 1.13 )range, -4.2 to 1.1( for lumbar spine and -1.64 ▒آ 0.89 )range, -3.9 to 1.9( for femoral neck that was interpreted as osteopenia in 16 )28.1percent( and 29 )50.9percent( patients, as well as osteoporosis in 28 )49.1percent( and 17 )29.8percent( cases, respectively. Both bone age and height age showed significant direct correlations with age at transplantation. There was no meaningful correlation between different types of kidney donors and bonemineral abnormalities in recipients.Conclusion. Our study revealed a relatively high prevalence of bone-mineral disorder in pediatric kidney recipients, which necessitates a routine program for periodic screening of these patients to facilitate early diagnosis of either persistent or evolving manifestations of disturbed mineral metabolism, especially ROD.
Descriptor : BRUCELLA SPP
Descriptor : BRUCELLOSIS
Descriptor : UREASE TEST
Descriptor : ACRIDINE ORANGE
Descriptor : BACTEC BLOOD CULTURE
Descriptor : IRAN
Added Entry : GHALEH GOLAB BEHBAHAN A
: LOTFI M
 
 
 
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