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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61684
Doc. No : 335A
Main Entry : MOMTAHEN M
Title & Author : DOUBLE BLIND RANDOMIZED CLINICAL TRIAL OF EZETIMIBE VERSUS ATORVASTATIN IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA [Article]; MOMTAHAN S.,KAZAZI A.S.A.D.
Title : IRANIAN HEART JOURNAL (IHJ)
Volume Number : , Vol.8 ؛ No.1
Date : , (2007)
page : : 33 - 37
Abstract : Objective- This randomized, double blind trial was designed to compare the efficacy and safety of ezetimibe, a new cholesterol-lowering agent with atorvastatin )Lipitor(, a potent cholesterol inhibitor derivative.Method- Between September 2004 and March 2005, a total of 120 hyperlipidemic patients, aged 28-80 years, were randomized to receive ezetimibe 10 mg or atorvastatin 10 mg orally daily for 8 weeks after a 4-week washout phase and diet on NCEP step n. Mean changes of serum lipoproteins after 4 and 8 weeks of drug therapy were measured and compared in both groups of patients.Results- Ezetimibe reduced LDLc and total cholesterol by a mean of 27percent and 16percent compared with 32percent and 24percent for atorvastatin, respectively. The difference was not statistically significant. Conclusion- Ezetimibe and atorvastatin both reduced LDLc and TC with no statistically significant difference.
Descriptor : EZETIMIBE
Descriptor : ATORVASTATIN
Descriptor : HYPERCHOLESTEROLEMIA
Added Entry : FARSAD F
: ABAS M
 
 
 
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