خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61731
Doc. No : 383A
Main Entry : GOVINDAN NEVIN K
Title & Author : EFFECT OF TOPICAL APPLICATION OF VIRGIN COCONUT OIL ON SKIN COMPONENTS AND ANTIOXIDANT STATUS DURING DERMAL WOUND HEALING IN RATS [Article]
Title : IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)
Volume Number : , Vol.9 ؛ No.2
Date : , (2010)
page : : 0 - 0
Abstract : The present study was undertaken to evaluate the effect of topically applied virgin coconut oil )VCO( on excision wound in rats. Three groups of female Sprague-Dawley rats each consisting of six animals were used. Group I was control, group II and III were treated with 0.5ml & 1.0ml VCO respectively, 24h after wound creation for 10 days. After the experimental period, healing property of VCO was evaluated by monitoring the time taken for complete epithelization )TCE(, levels of various parameters of the wound granulation tissue. Collagen solubility pattern, glycohydrolases activity, and histopathology of the granulation tissue were also done. The antioxidant status during wound healing was monitored for 14 days. VCO treated wound healed much faster as indicated by a decreased TCE and higher levels of various skin components. Pepsin soluble collagen showed a significant increase in VCO treated wound indicating a higher collagen cross linking. Glycohydrolases activities were also found to be increased due to higher turnover of collagen. Antioxidant enzyme levels, GSH and MDA levels were found to be increased on the 10th day of post wounding, which were later found to be reversed to normal levels on day 14 in treated wounds. Lipid peroxide levels was found to be lower in treated wounds. Histopathological study showed an increase in fibroblast proliferation and neo-vascularisation in VCO treated wound compared to control. This beneficial effect of VCO can be attributed to the cumulative effect of various biologically active minor components present in it.
Descriptor : CORD CLAMP
Descriptor : DELIVERY TYPE
Descriptor : HEMATOCRIT
Descriptor : HEMOGLOBIN
Added Entry : RAJAMOHAN T.H
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)