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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61737
Doc. No : 389A
Main Entry : FAKHER SH
Title & Author : EFFECT OF VITAMINS A, E, C AND OMEGA-3 FATTY ACIDS ON LIPID PEROXIDATION IN STREPTOZOTOCIN INDUCED DIABETIC RATS [Article]; ZERAATI H.A.,JAVADI E.,SADEGHI M.R.,MOSTAFAVI E.,FATEHI F.
Title : IRANIAN JOURNAL OF PUBLIC HEALTH
Volume Number : , Vol.36 ؛ No.2
Date : , (2007)
page : : 58 - 63
Abstract : Background: To assess the effect of supplementation with vitamins A, E and C and w-3 fatty acids on lipid peroxidation in streptozotocin )STZ( induced diabetic rats.Methods: Sixty four male wistar rats weighting 250g were divided into four groups as normal control, diabetic control, diabetic with vitamin A, E as well as C supplementation and diabetic with w-3 fatty acids supplementation. After four weeks of treatment the rats were anesthetized and malondialdehyde )MDA( levels were investigated in blood samples, liver and heart homogenate.Results: In diabetic 3.0rats MDA level in plasma, liver and heart was significantly more elevated than normal control rats )P<0.05(. Vitamin A, E and C supplementation caused significant decrease in plasma, liver and heart MDA )P<0.05(. A significant decrease in heart MDA )P< 0.05( was observed in diabetic rats with w-3 fatty acids supplementation. Conclusion: Supplementation of vitamin A, E and C and w-3 fatty acids was found to decrease lipid peroxidation to some extent in diabetic rats and they can be valuable candidates in the treatment of the complications of diabetes.
Descriptor : VITAMIN C
Descriptor : VITAMIN E
Descriptor : VITAMIN A
Descriptor : OMEGA3 FATTY ACID
Descriptor : MALONDIALDEHYDE
Added Entry : JALALI M
: TABEI S.M.B
 
 
 
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