خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61738
Doc. No : 390A
Main Entry : KIASALARI Z
Title & Author : EFFECT OF WITHANIA SOMNIFERA ON LEVELS OF SEX HORMONES IN THE DIABETIC MALE RATS [Article]
Title : IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE
Volume Number : , Vol.7 ؛ No.4
Date : , (2009)
page : : 163 - 168
Abstract : Background: There are evidences regarding the prevalence of dysfunction in sexual function and behavior in diabetic people. Experimental studies revealed a positive effect of withania somnifera on sexual function and behaviors.Objective: In this research, the effect of withania somnifera on sexual function in diabetic male Wistar rats was assessed by measuring the serum levels of testosterone, progesterone, estrogen, FSH and LH.Materials and Methods: Experimental diabetes mellitus type I was induced by intraperitoneal injection of a single dose )60 mg/kg( of streptozotocin )STZ( in Wistar male rats. Oral withania somnifera root was given in pelleted food at ratio of 6.25percent for 4 weeks. The levels of gonadadotropic hormones )LH, FSH(, progesterone, estrogen and testosterone in animals عserum were determined after 4 weeks in all groups. Results: Withania somnifera root was effective in lowering FSH serum level in somnifera-treated animals compared to controls )p<0.05( in both diabetic and non-diabetic groups, whereas progesterone )p<0.05(, testosterone )p<0.05( and LH levels )p<0.001( were significantly higher in non-diabetic treated animals. Oral somnifera root was also able to reverse the reductive effect of diabetes on the progesterone. The estrogen level did not show any significant difference in any of the groups.Conclusion: It is suggested that withania somnifera may have a regulatory effect on diabetes-induced change of the levels of gonadal-hormones, especially progesterone, in male rats. Nevertheless, somnifera is apparently only able to diminish FSH serum level in intact animals.
Descriptor : WITHANIA SOMNIFERA
Descriptor : DIABETES
Descriptor : SEX HORMONES
Descriptor : RAT
Added Entry : KHALILI MOHSEN
: AGHAEI MAHBOUBEH
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)