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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61883
Doc. No : 537A
Main Entry : FALAHZADEH M.H
Title & Author : HEMATURIA IN PATIENTS WITH BETA-THALASSEMIA MAJOR [Article]; RASTGAR SH.,DERAKHSHAN ALI,FALAHZADEH M.A.
Title : IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)
Volume Number : , Vol.4 ؛ No.2
Date : , (2010)
page : : 133 - 136
Abstract : Introduction: Our information about renal involvement in betathalassemia major is limited. Recently, few studies have reported proteinuria, hypercalcuria, phosphaturia, and oversecretion of tubular damage markers; however, hematuria has not yet been meticulously studied in these patients. We investigated hematuria in patients with beta-thalassemia major.Materials and Methods: Urinalysis was performed in 500 patients with beta-thalassemia major under a regular blood transfusion program. In those with hematuria )at least 3 to 5 erythrocytes per high-power field( a second urinalysis was done at the next transfusion time.Results: The patients ranged in age from 6 months to 32 years. The male-female ratio was 1.05:1. Hematuria was detected in 55 )10.6percent(, including 9.8percent of those younger than 20 years and 20.0percent of those older than 20 years. Hematuria was persistent in 79.2percent of the second urinalyses. Sixty-four percent of the patients with hematuria were females. A blood transfusion program had been started during the first year of life in 81percent percent of the patients with hematuria. Sterile pyuria was detected in 4percent and proteinuria in 16percent of the patients with hematuria, while these figures in patients without hematuria were 2.1percent )P=.56( and 1.4percent )P=.002(, respectively.Conclusions. We found that in patients with beta-thalassemia major, the risk of hematuria rises with age. Moreover, proteinuria seems to be more common in those with hematuria. Further studies are needed to ascertain the importance of these findings.
Descriptor : BETA-THALASSEMIA
Descriptor : PROTEINURIA
Descriptor : URINALYSIS
Descriptor : DEFEROXAMINE
Descriptor : IRON OVERLOAD
Added Entry : FALAHZADEH M.K
: SHAHRIARI MAHDI
 
 
 
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