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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61929
Doc. No : 584A
Main Entry : NILI F.*,
Title & Author : HYPOGLYCEMIA IN SICK PRETERM INFANTS AND THE THERAPEUTIC EFFECT OF 12.5 DEXTROSE IN WATER COMPARED WITH 10 DEXTROSE IN WATER [Article]
Title : ACTA MEDICA IRANICA
Volume Number : , Vol.43 ؛ No.3
Date : , (2005)
page : : 182 - 186
Abstract : Neonatal hypoglycemia is common and its prompt management is important to reduce neurological sequelae. To determine the effect of two different glucose concentrations of intravenous )IV( fluid therapy in the incidence of hypoglycemia in sick premature infants, 200 preterm infants weighing 1500-2500 g were selected and randomly assigned into two groups. Group 1 received 10percent dextrose in water )DW( and for group 2 we used 12.5percent DW with recommended fluid volume according to the infantعs condition. First blood glucose sample was obtained during 2-3 hours of life before starting IV therapy and the two others were measured between 4-24 hours of life after starting IV fluid therapy. Plasma glucose < 36 mg/dl during 2-3 hours of life and level below 45 mg/dl between 4-24 hours of life were considered as hypoglycemia. Birth weight, gestational age and type of diseases in two groups were matched. Although there was no difference between volume of fluid, statistical differences were found to be significant between amounts of calories )P= 0.000( and dextrose )P= 0.000( received in two groups. We detected 15 and 30 cases of hypoglycemia in group 1 and 2, respectively. After starting IV fluid therapy, the incidence of hypoglycemia decreased especially in group 2 and comparison of cases with two consecutive low plasma glucose in two groups showed significant difference )P= 0.024, relative risk= 2.67(. We recommend 12.5percent DW when initiation of peripheral IV therapy is indicated in sick preterm infants weighing 1500-2500 g, especially when restriction of fluid is mandated.
Descriptor : HYPOGLYCEMIA
Descriptor : INTRAVENOUS FLUID THERAPY
Descriptor : PRETERM INFANTX
Added Entry : GHAFURI M.
 
 
 
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