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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61987
Doc. No : 645A
Main Entry : NOUROUZIAN M
Title & Author : IS HYPERHOMOCYSTEINEMIA A RISK FACTOR FOR ISCHEMIC STROKE? A CASE CONTROL STUDY [Article]; AKHOUNDZADEH SH.*
Title : IRANIAN JOURNAL OF PSYCHIATRY
Volume Number : , Vol.3 ؛ No.2
Date : , (2008)
page : : 75 - 78
Abstract : Objective: The results of the previous studies on the correlation between plasma levels of Homocysteine )Hcy( and ischemic stroke have been controversial. The aim of the present study is to investigate this correlation by meticulously observing risk factors for the ischemic stroke as well as factors affecting the plasma levels of Hcy.Method: A case-control study was conducted between 2005-2006 with 30 cases )55-84 years of age( who had never had a Transient Ischemic Attack )TIA( all within one week of their first-ever ischemic stroke The 30 control subjects who had never had a stroke or TIA episode were selected from the orthopedics ward of the same hospital. The cases and controls were paired based on age, sex, cardiac disease, hypertension and smoking status and were adjusted for other risk factors. Their total non-fasting plasma Hcy level was determined using the High-Performance Liquid Chromatography )HPLC( method.Results: The mean plasma levels of Hcy was significantly higher in cases than controls )mean=20.79▒آ11.938 versus 14.45▒آ8.028 mol/L; P<0.017(. After using the multivariate logistic regression model, a significant correlation was found between plasma levels of Hcy and stroke )OR=1.149 with 95percent CI of 1.032-1.280 for each 1 mol/L increment(.Conclusion: The results indicate that there is a correlation between increasing plasma Hcy level and ischemic stroke; however, future research is needed to prove the causal relationship between the two.
Descriptor : BRAIN ISCHEMIA
Descriptor : CEREBROVASCULAR DISORDERS
Descriptor : HOMOCYSTEINE
Descriptor : RISK FACTORS
Added Entry : SINA A.H
: MASOUD RAD B
 
 
 
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