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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 61990
Doc. No : 648A
Main Entry : HEDAYATI GOUDARZI A.K
Title & Author : IS THE USAGE OF DAILY DOSAGE OF VITAMIN D (400 IU ) AND CALCIUM (1200 MG) SUFFICIENT IN PREMENOPAUSAL WOMEN WITH BREAST CANCER UNDERGOING ADJUVANT CHEMOTHRAPY? (STUDY OF 157 PATIENTS IN TABRIZ) [Article]; HEDAYATI GOUDARZI A.M
Title : INTERNATIONAL JOURNAL OF HEMATOLOGY-ONCOLOGY AND STEM CELL RESEARCH (IJHOSCR)
Volume Number : , Vol.3 ؛ No.4
Date : , (2009)
page : : 14 - 15
Abstract : Purpose: Due to socially specific dressing and routine consumption of sun avoidance behaviors, vitamin D onsumptio is a common women healthy problem in north west of iran. vit D onsumptio is associated with increased breast cancer risk and decreased breast cancer survival. The purpose of this study was to determined the onsumptio of vit D onsumptio, as measurable by serum vit D )25-OH D( and calcium in 157 premenopausal women with breast cancer at initiation of adjuant onsumption for breast cancer and after 1 and 2 years of vit D and calcium supplementation.Patients and methods: The study included 157 premenopausal women [mean age 44 years )19-52([ from the north west of Iran with stage 1-3 breast cancer who received adjuant onsumption. All patients were prescribed vit D3 and calcium carbonate )400IU/d, 1200mg/d(. At baseline and 12 and 24 months of treatment, blood was collected and analyzed )radioimmunoassay( in batches for serum 25-OH D )VIT D3( and calcium. Vit D onsumptio was defined as serum vit D3 less than 20ng/ml, insufficiency as 20-29 ng/ml and sufficiency as 30 ng/ml or greater, and lower limit of corrected calcium was 8/5 mg/dl.In the end of first year, in patient with vitD onsumptio and hypocalcemia, increased consumption of vit D 800 iu/day and calcium to 1500 mg/day.Results: At baseline 69percent of patients were vit D onsumpti )31percent sever D3 defecient and 38percent vitD3 insfficient( and 32percent hypocalcemic, after 1 year supplementation of vit D and Calcium )400 iu/d, 1200 mg/d( less than 19percent of patients with vit D onsumptio achieved normal limit vit D3, and serum calcium normalized in 20percent of hypocalcemic patient in baseline. In the end of second year of supplementation of vit D3 and calcium )800 iu/d, 1500 mg/d(, vit D onsumptio in 17percent and hypocalcemia in 2percent of patients not corrected.Conclusion: Vit D onsumptio and hypocalcemia is highly onsumpti in women with breast cancer. The current recommended dietary allowance of vit D and calcium )400 iu/d, 1200 mg/d( is to low to increase serum vit D greater than 30 ng/ml and corrected serum calcium greater than 8/5mg/dl. We recommended the onsumption of vit D increased to 800-1000 iu/d and calcium to 1500mg/day, for bone health and improved survival of patients. Because our results indicate clearly that vit D 400 iu/d and calcium1200mg/d has minimal efficacy in correcting this wide spreed problem.
Descriptor : BREAST CANCER
Descriptor : VITAMIN D
Descriptor : CALCIUM
Descriptor : PREMENOPAUSE
Descriptor : CHEMOTHERAPY Purpose: Due to socially specific dressing and routine consumption of sun avoidance behaviors
Descriptor : vitamin D onsumptio is a common women healthy problem in north west of iran. vit D onsumptio is associated with increased breast cancer risk and decreased breast cancer survival. The purpose of this study was to determined the onsumptio of vit D onsumptio
Descriptor : as measurable by serum vit D (25-OH D) and calcium in 157 premenopausal women with breast cancer at initiation of adjuant onsumption for breast cancer and after 1 and 2 years of vit D and calcium supplementation.Patients and methods: The study included 157 premenopausal women [mean age 44 years (19-52)] from the north west of Iran with stage 1-3 breast cancer who received adjuant onsumption. All patients were prescribed vit D3 and calcium carbonate (400IU/d
Descriptor : 1200mg/d). At baseline and 12 and 24 months of treatment
Descriptor : blood was collected and analyzed (radioimmunoassay) in batches for serum 25-OH D (VIT D3) and calcium. Vit D onsumptio was defined as serum vit D3 less than 20ng/ml
Descriptor : insufficiency as 20-29 ng/ml and sufficiency as 30 ng/ml or greater
Descriptor : and lower limit of corrected calcium was 8/5 mg/dl.In the end of first year
Descriptor : in patient with vitD onsumptio and hypocalcemia
Descriptor : increased consumption of vit D 800 iu/day and calcium to 1500 mg/day.Results: At baseline 69
 
 
 
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