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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62037
Doc. No : 696A
Main Entry : RAMEZANI AMITIS
Title & Author : METABOLIC ABNORMALITIES IN HIV-POSITIVE PATIENTS RECEIVING HIGHLY ACTIVE ANTIRETROVIRAL THERAPY [Article]; GACHKAR L.,JAM SARA,ESLAMIFAR A.,YAGHMAEI F.,NEMATI K.,AGHAKHANI A.
Title : IRANIAN JOURNAL OF PATHOLOGY (IJP)
Volume Number : , Vol.2 ؛ No.4
Date : , (2007)
page : : 154 - 158
Abstract : Background and Objective: Dyslipidemia has become a common problem in human immunodeficiency virus )HIV( disease, especially in patients on combination antiretroviral therapy. In this study we aimed to determine the prevalence of dyslipidemia and metabolic abnormalities in 2 groups of HIV infected patients receiving highly active antiretroviral therapy )HAART( and antiretroviral-naive patients.Patients and Methods: Forty HIV infected patients treated by HAART as a case group )6 females and 34 males( with a mean age of 40.7▒آ10 years and 15 HIV naأطve as a control group )2 females and 13 males( with a mean age of 38.40▒آ8.3 enrolled in this study. The two groups were well matched in respect to age, sex and CD4 cell counts. A standardized questionnaire with epidemiological, clinical, and therapeutic data was completed by physicians. Blood samples were obtained for metabolic measurements. CD4 positive cell count was measured by f lowcytometry.Results: Levels of total cholesterol, triglycerides, LDL, HDL, lactate, and FBS were elevated in 24percent, 37percent, 3.7percent, 44.4percent, 29.6percent and 11percent of patients respectively. There was a significant difference regarding mean total cholesterol and LDL between treated group and controls )p<0.05(. There was also no significant difference between treated group and controls regarding triglyceride, HDL, lactate and FBS levels.Conclusion: Our study demonstrated that metabolic abnormalities are relatively common in HIV-infected patients receiving HAART. Therefore, it is recommended to screen the HIV infected patients on HAART for metabolic disorders, potential of morbidity, and possible long-term cardiovascular risk factors.
Descriptor : DYSLIPIDEMIA
Descriptor : HYPERGLYCEMIA
Descriptor : HIV
Descriptor : HIGHLY ACTIVE ANTIRETROVIRAL THERAPY
Added Entry : MOHRAZ M
: BANIFAZL M
 
 
 
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