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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62059
Doc. No : 719A
Main Entry : ARDAKANI A.M
Title & Author : NUTRIGENOMICS AND CANCER [Article]
Title : AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY (AJMB)
Volume Number : , Vol.1 ؛ No.1
Date : , (2009)
page : : 9 - 17
Abstract : Cancer incidence is projected to increase in the future and an effectual preventive strategy is required to face this challenge. Alteration of dietary habits is potentially an effective approach for reducing cancer risk. Assessment of biological effects of a specific food or bioactive component that is linked to cancer and prediction of individual susceptibility as a function of nutrientnutrient interactions and genetics is an essential element to evaluate the beneficiaries of dietary interventions. In general, the use of biomarkers to evaluate individualعs susceptibilities to cancer must be easily accessible and reliable. However, the response of individuals to bioactive food components depends not only on the effective concentration of the bioactive food components, but also on the target tissues. This fact makes the response of individuals to food components vary from one individual to another.Nutrigenomics focuses on the understanding of interactions between genes and diet in an individual and how the response to bioactive food components is influenced by an individualعs genes. Nutrients have shown to affect gene expression and to induce changes in DNA and protein molecules. Nutrigenomic approaches provide an opportunity to study how gene expression is regulated by nutrients and how nutrition affects gene variations and epigenetic events. Finding the components involved in interactions between genes and diet in an individual can potentially help identify target molecules important in preventing and/or reducing the symptoms of cancer.
Descriptor : BIOACTIVE FOOD COMPONENTS
Descriptor : BIOMARKER
Descriptor : CANCER PREVENTION
Descriptor : NUTRIGENETICS
Descriptor : NUTRIGENOMICS
Added Entry : I SEPIDEH
 
 
 
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