خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62109
Doc. No : 770A
Main Entry : EL FAKHARANY E.M
Title & Author : POTENTIAL ACTIVITY OF CAMEL MILK-AMYLASE AND LACTOFERRIN AGAINST HEPATITIS C VIRUS INFECTIVITY IN HEPG2 AND LYMPHOCYTES [Article]; HAROUN B.M.,REDWAN E.R.M
Title : HEPATITIS MONTHLY
Volume Number : , Vol.8 ؛ No.2
Date : , (2008)
page : : 101 - 109
Abstract : Background and Aims: To exploring which camel milk proteins, have the ability to inhibit and/or blocking the hepatitis C virus )HCV( entry and replication inside the cells system.Methods: Using human peripheral blood mononuclear cells )PBMCs( and hepG2 cells system, three experiments were setup: 1( cells treated with amylase or lactoferrin then infected with HCV; 2( HCV treated with amylase or lactoferrin then used to infect the cells; and 3( HCV infected cells were treated with amylase or lactoferrin. RNA was extracted, RTPCR and nested PCR were run, in addition to immune-staining the cells to localize the viral molecule within the cells foci.Results: Camel milk-amylase and lactoferrin were in vitro tested the ability to inhibit the HCV entry and replication inside the human peripheral blood and hepG2. Amylase could not able to inhibit nor blocking the viral replication.However, lactoferrin demonstrate a clear ability to inhibit the viral entry into both cells system when pre-interact with the virus, but fault to protect the cells before infection. The virus replication inside the cells was completely blocked only when the infected cells were treated with lactoferrin.Conclusions: Camel lactoferrin was demonstrated a remarked in vitro ability to completely inhibit the HCV entry into PBMC, hepG2 and replication inside those cells system.
Descriptor : CAMEL MILK
Descriptor : AMYLASE
Descriptor : LACTOFERRIN
Descriptor : HEPATITIS C
Descriptor : INHIBITION
Descriptor : IN VITRO ASSAY
Added Entry : TABLL A
: ABD EL WAHAB A
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)