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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62125
Doc. No : 786A
Main Entry : MERAT S
Title & Author : PREVALENCE OF FATTY LIVER DISEASE AMONG TYPE 2 DIABETES MELLITUS PATIENTS AND ITS RELATION TO INSULIN RESISTANCE [Article]; ALIZADEH Z.,SEDIGHI N.,MANSOURNIA N.,GHORBANI A.,MALEKZADEH R.
Title : MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD)
Volume Number : , Vol.1 ؛ No.2
Date : , (2009)
page : : 74 - 79
Abstract : Background: A substantial proportion of the mortality in patients with type 2 diabetes mellitus )T2DM( is related to non-alcoholic fatty liver disease )NAFLD( and its complications. Insulin resistance is a major etiologic factor for the development of fatty liver. We aimed to study the prevalence of NAFLD among T2DM patients and its relation to insulin resistance.Methods: Patients with T2DM that were referred to a tertiary referral center in Tehran from February 2003 to August 2005 were evaluated. Patients with characteristic findings on ultrasonography were considered as having fatty Livers. The Homeostasis Model Assistant-Insulin Resistance )HOMA-IR( and Quantitative Insulin Sensitivity Check Index )QUICKI( were calculated as measures of insulin resistance.Results: Of the 172 patients included in the study, 96 )55.8percent( had evidence of fatty livers, 6 of which )3.5percent of total( presented with elevated liver enzymes. BMI and triglyceride levels in the fatty liver group were significantly higher than patients with normal livers )p=0.002 and 0.036, respectively(. The HOMA-IR and QUICKI indexes were not significantly different between the two groups.Conclusion: Fatty liver is a common finding among T2DM patients. The degree of insulin resistance does not appear to be predictive of fatty liver among this population
Descriptor : NON-ALCOHOLIC STEATOHEPATITIS
Descriptor : TYPE 2 DIABETES
Descriptor : INSULIN RESISTANCE
Added Entry : YARAHMADI S
: TAHAGHOGHI S
 
 
 
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