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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62157
Doc. No : 818A
Main Entry : KARIMI GH.R.
Title & Author : PROTECTIVE EFFECT OF ROSMARINUS OFFICINALIS L. ESSENTIAL OIL AGAINST FREE RADICAL-INDUCED ERYTHROCYTE LYSIS [Article]
Title : IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume Number : , Vol.1 ؛ No.4
Date : , (2005)
page : : 231 - 236
Abstract : The oxidative hemolysis of rat erythrocytes induced by 2,2ع-azobis)ع2- amidinopropane( )AAPH( and its inhibition by rosemary essential oil was studied. Different concentrations )0.178, 0.357, 0.534 and 0.712 ?l/ml( of the essential oil showed no significant hemolysis compared to phosphate buffer solution. AAPH )25 mM and 50 mM( induced hemolysis in a time-dependent manner. Diff e r e n t concentrations of the essential oil inhibited hemolysis induced by 25 mM AAPH. However, in the presence of 50 mM of AAPH, only the two higher concentrations )0.534 and 0.712 ?l/ml( of the essential oil inhibited hemolysis. Addition of essential oil 2 or 3 h after incubation with AAPH had no significant effects on the time course of cell lysis. It is concluded that, in addition to its well-established antioxidant effects, rosemary essential oil displays cytoprotective properties.
Descriptor : AAPH
Descriptor : HEMOLYSIS
Descriptor : ROSMARINUS OFFICINALIS
Added Entry : HASANZADEH M.
: MEHRI S.
 
 
 
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