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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62182
Doc. No : 843A
Main Entry : KAHNOUJ M
Title & Author : RELATIONSHIP BETWEEN CALCIUM-PHOSPHORUS PRODUCT AND SEVERITY OF VALVULAR HEART INSUFFICIENCY IN PATIENTS UNDERGOING CHRONIC HEMODIALYSIS [Article]; ZAEIM A.,SHEYKH VATAN M
Title : THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER
Volume Number : , Vol.5 ؛ No.2
Date : , (2010)
page : : 78 - 82
Abstract : Background: Recent interests have mainly focused on the roles of serum calcium and phosphorus and their product )Ca-P product( in the development of valvular heart disease. The present study assessed the relationship between the Ca-P product and the severity of valvular heart disease in end-stage renal disease )ESRD( patients undergoing chronic hemodialysis.Methods: This cross-sectional study reviewed the clinical course of 72 consecutive patients with the final diagnosis of ESRD candidated for chronic hemodialysis. The severity of valvular heart disease was determined using M-mode two-dimensional echocardiography. The serum calcium and phosphate values adopted were those values measured on the day between the two consecutive dialyses, and the Ca-P product was calculated.Results: The most common causes of ESRD were diabetic nephropathy, malignant hypertension, and chronic glomerulonephritis. The mean Ca-P product level in the dialysis patients was 50.4▒آ17.78 mg2/dL2. The receiver-operator characteristic )ROC( curve illustrated that a Ca-P product level > 42 mg2/dL2 was the optimal value in terms of sensitivity and specificity for predicting the presence of valvular insufficiency. Aortic insufficiency was directly associated with a high Ca-P product value after adjustment for age, gender, serum albumin, diabetes, hypertension, hyperlipidemia, coronary artery disease, and serum creatinine )b=0.412, SE=158, p value=0.011(.Conclusion: A positive relationship between the Ca-P product value and the severity of aortic insufficiency is expected. Achieving an appropriate control of the Ca-P product level may decrease aortic valve calcification and improve the survival of patients on chronic hemodialysis.
Descriptor : HEART VALVE DISEASE
Descriptor : RENAL DIALYSIS
Descriptor : KIDNEY FAILURE
Descriptor : CALCIUM
Descriptor : PHOSPHORUS
Added Entry : MASOUMI MOHAMMAD
: NADERINASAB A
 
 
 
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