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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62208
Doc. No : 870A
Main Entry : ARDESTANI S.K.
Title & Author : RESTORATIVE EFFECT OF VITAMIN E ON SOME IMMUNOLOGICAL PARAMETERS OF SUB-LETHAL G -IRRADIATED BALB/C MICE [Article]
Title : IRANIAN BIOMEDICAL JOURNAL
Volume Number : , Vol.4 ؛ No.1
Date : , (2000)
page : : 51 - 55
Abstract : Elevated amount of the free radicals due to ionizing radiation causes deteriorating damage on immune system. Therefore, we made attempts to investigate the protective effect of vitamin E )vit-E(, a biological antioxidant in BALB/c mice, so as to find an affordable prophylactic supplementation for individuals who are at risk. Several groups of mice were selected and exposed to sub-lethal g -irradiation with or without vit-E supplementation. At the end of exposure, mice were immunized by either live attenuated Brucella melitensis vaccine or sheep red blood cell )SRBC(. Consequently, the following parameters were assayed: specific antibody response, delayed type hypersensitivity and lymphocyte proliferation. We showed that vit-E supplementation restored the immune response in g -irradiated mice. These findings might have implications for individuals who are at risk of exposure to ionizing radiation. Iran. Biomed.
Descriptor : VITAMIN E
Descriptor : IMMUNE RESPONSE
Descriptor : G -IRRADIATION
Descriptor : BALB/C MICE
Added Entry : AMANI M.,
: KARIMINIA AMINA
 
 
 
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