خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62321
Doc. No : 983A
Main Entry : DOUSTAR Y
Title & Author : THE EFFECT OF TREADMILL EXERCISE ON EXPERIMENTAL DIABETIC HEPATOPATHY IN RATS [Article]; HASHEMI SEYED MEHRDAD
Title : MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY
Volume Number : , Vol.19 ؛ No.1
Date : , (2009)
page : : 25 - 32
Abstract : Background: Regular exercise by increasing insulin sensitivity and improving the glucose uptake and lowering body adiposity is a powerful non-pharmacological tool for prevention and treatment of diabetes mellitus. Diabetic hepatopathy is the main cause of liverilure. The purpose of this study was to evaluate the effect of regular exercise on diabetic hepatopathy.Materials and methods: In this experimental study, 56 wistar male rats with approximate age of 12 weeks and 200-300g weight were allocated into two equal groups of treatment and control. For induction of diabetes, these two groups were injected by streptozotocin )50 mg/kg( intraperitoneally. The treatment group was kept in normal conditions of management with regular exercise )treadmill( as 5 days a week, an hour every day, for 12 weeks. In control group, subjects have normal conditions without any physical activity and regular exercise. After 12 weeks, liver tissues were sampled in both groups and 5-6 micron tissue sections were prepared through H&E staining method.Results: Histopathological study in control group showed hepatosclerosis, central vein perivascular cuffing of mononuclear inflammatory cells, hepatocellular degeneration, sclerosing hyaline necrosis, apoptosis, dense perisinusoidal, and periportal and perivenular fibrosis. Mild pathological changes were observed in treatment group and significant differences were observed between two groups.Conclusion: Treadmill exercise is capable in reduction of pathological changes and improves diabetic hepatopathy to near normal histology.
Descriptor : DIABETIC HEPATOPATHY
Descriptor : TREADMILL EXERCISE
Descriptor : DIABETES MELLITUS
Added Entry : ,MOHAMMADI MOSTAFA
: MOHAJERI D
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)