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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62330
Doc. No : 992A
Main Entry : JAZAYERI MARYAM
Title & Author : THE EFFECTS OF EIGHT-WEEK TREATMENT WITH HIGH DOSE VITAMIN E ON SERUM CHOLESTEROL AND TRIGLYCERIDE LEVEL OF PATIENTS WITH SCHIZOPHRENIA ON OLANZAPINE: A PLACEBO CONTROLLED STUDY [Article]; HASHEMIAN FARSHAD,ZAHIR ALDIN A.R.,AKHOUNDZADEH SH.,RAEISI FIROUZEH,GOLCHIN K.,AFGHAH S.,BAJOGHLI H.
Title : IRANIAN JOURNAL OF PSYCHIATRY
Volume Number : , Vol.3 ؛ No.1
Date : , (2008)
page : : 43 - 45
Abstract : Objective: To study the effects of a high dose alpha-tocopherol on serum total cholesterol )TC(, triglyceride )TG(, and the high density lipoprotein )HDL( levels of patients with schizophrenia receiving olanzapine.Method: Thirty six adults diagnosed with schizophrenia based on DSM-IV who were taking olanzapine for a minimum of thirty days entered this eight-week, double blind, and placebo-controlled study. Patients were randomized to receive alpha-tocopherol 400IU or placebo capsules twice a day for 2 weeks, then three times a day for 6 more weeks. Fasting total cholesterol )TC(, triglyceride )TG(, and HDL levels were measured at the baseline and weeks 4 and 8.Results: TC, TG and HDL levels did not change significantly during this study. There were no significant differences in TC, TG and HDL levels between the two groups at the baseline and weeks 4 and 8.Conclusion: High-dose vitamin may not improve triglyceride and cholesterol levels in patients who are already on olanzapine. Further studies with greater number of patients and for a longer duration are needed.
Descriptor : CHOLESTEROL
Descriptor : OLANZAPINE
Descriptor : SCHIZOPHRENIA
Descriptor : TRIGLYCERIDE
Descriptor : VITAMIN E
Added Entry : BAROYANT SALMASI F
: GHAELI P
 
 
 
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