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library name : انستیتو تغذیه دانشگاه علوم پزشکی شهید بهشتی
Material Type : Latin Articles
Language of Document : English
Record Number : 62452
Doc. No : 1114A
Main Entry : TAMADONDAR M
Title & Author : 25 (OH) VITAMIN-D DEFICIENCY IN CHRONIC HEMODIALYSIS PATIENTS AND ITS CORRELATIONS WITH INTACT PTH, CALCIUM AND PHOSPHORUS (ORAL PRESENTATIONS: O106) [Article]; SAMADIAN F.,FIROUZAN A.,ALIPOUR ABEDI B.,MOUMCHI F.,TABKHI N.,NAFAR M.,EYN ELAHI B.
Title : IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)
Volume Number : , Vol.3 ؛ No.SUPPLEMENT 1
Date : , (2009)
page : : 4 - 4
Abstract : Introduction. Vit-D not only has essential effects on bone biology but also there are convincing evidences about the protective role of vitamin D in overall and cardiovascular mortality, hypertension, LVH, and malignancies. Based on recent studies, vitamin D deficiency is quite common in chronic renal failure and ESRD patients in North America and European countries. Concerning the impact of nutrition, climate, and culture, this study was conducted to evaluate the frequency of vitamin D deficiency and its correlation with other clinical and laboratory characteristics of our chronic hemodialysis patients.Method. In chronic hemodialysis patients of our center, plasma level of 25 )OH( vitamin-D was measured and its relation with other variables like Ca, P, intact PTH )iPTH(, age, sex, duratiob on chronic hemodialysis, Hb, WBC, PLT, and serum albumin were evaluated. Patients were divided into 3 groups; 1: Vit-D level ▒آ 10 ng/ ml, as severe vit-D deficiency; 2: Vit-D level between 10 and 30 ng/ml, as moderate Vit-D deficiency; and 3: Vit-D level > 30 ng/ml, as normal Vit-D level. Then, we evaluated all variables according to these categories. Result. A total of 46 patients )27 males and 19 females( were evaluated in this study. The average of Vit-D was 20.85 ▒آ 9.4 mg/l )minimum level, 5.6 ng/ml; maximum level, 43.6 ng/ml(. A total of 67percent of the patients had moderate Vit-D deficiency, 11percent had severe Vit-D deficiency, and 22percent had normal level. Comparing severe and moderate Vit-D deficiency groups, there were not any significant differences, except sex and Hb level. Of 5 patients in severe vit-D deficiency group, 20percent were male and 80percent were female; in contrast, in moderate vit.D deficiency group, 68percent were male and 32percent were female )P < 0.05(. In severe vit-D deficiency group, mean Hb level was 8.5 ▒آ 1.5; in contrast, in moderate vit-D deficiency group, the mean Hb level was 10.8 ▒آ 2.0 )P < 0.05(. According to iPTH level, all patients were divided into 2 groups, 1: آذ ]300 pg/ml )12 patients([ and 2: [>300 pg/ml )34 patients([. Comparing these 2 groups, the Vit-D level and sex had significant differences )P <0.05(. The averages of Vit-D level in low and high PTH groups were 16 ▒آ 7 ng/ml and 22.5 ▒آ 7.5, respectively. The odd of finding low PTH in vitamin D deficient group was 2. In low PTH group, 92percent were male while, 47percent were male in high PTH group )odds ratio = 9(. Conclusion. Our data shows that frequency of 25 OHD3 deficiencies in our hemodialysis patients is very high )78percent(. Also, it demonstrates that the odds of Vit-D deficiency in patients with lower iPTH and women are more than the other groups. Also, we found that the frequency of lower iPTH in men was more than women
Descriptor : ی‌هدریش‍ ی‌تیافک‍ دوخ‍
Descriptor : ه‌دش‍ ک‌رد س‌رتسا
Descriptor : از ت‌سخن‍ ن‌اردام‍
Added Entry : AHMADPOUR P
: POURREZA GHOLI F
 
 
 
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